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Updated: Apr 17, 2026

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
Published on: June 3, 2018
[Glaucoma: trends in the study of its etiology]
Juan Carlos Serna-Ojeda1, Elsa María Flores-Reyes1, Curt Hartleben-Matkin1
1Departamento de Glaucoma, Instituto de Oftalmología «Conde de Valenciana», México, D.F.
Background:
There are different etiologies related to glaucoma, with the involvement of different systems in the origin and development of the disease.
Methods:
We performed a literature review.
Results:
The data is divided, with an emphasis on five main topics: systemic disease, neurodegenerative disease, genetic disease, immunological disease, and aging of the trabecular meshwork. Older and recent important findings of each subject are reported to establish a relationship with glaucoma, and mention is made of some of the current research lines.
Conclusion:
Glaucoma is a multifactorial disease with complex interaction of events at various levels of the organism. Study of the etiology should guide the search for new therapies.
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