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Polymerase chain reaction for detection of dissemination in gastric lymphoma
D Cunningham1, T Hickish, R D Rosin
1Ludwig Institute for Cancer Research, St Mary's Hospital Medical School, London.
Abstract:
The polymerase chain reaction (PCR) was used to detect malignant lymphoma cells with the bcl-2 gene rearrangement in the peritoneal washings and bone marrow of a patient with an apparently localised gastric lymphoma. After four courses of cytotoxic drug treatment the cells could no longer be detected in either site. PCR is a useful addition to the staging investigations of non-Hodgkin lymphoma and can also be used to monitor response to treatment.
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