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[Children with autism and related contact disorders: medical aspects]
Insights
Extensive medical evaluations are crucial for children with infantile autism or atypical developmental disorders, as 8 of 15 examined had detectable chromosomal, neurological, or biochemical disorders.
Area of Science:
- Pediatric neurology
- Developmental pediatrics
- Genetics
Context:
- Infantile autism and atypical pervasive developmental disorders (PDDs) are complex neurodevelopmental conditions.
- Somatic aspects significantly influence the presentation and management of these disorders in children.
- Understanding underlying medical factors is essential for comprehensive care.
Purpose:
- To review key hereditary, perinatal, and neurological factors associated with infantile autism and atypical PDDs.
- To present findings from medical examinations of children diagnosed with these disorders.
- To emphasize the importance of thorough medical assessment in diagnosing and managing autism spectrum disorder (ASD) and related conditions.
Summary:
- A review of hereditary, perinatal, neurological, and neurophysiological factors in infantile autism and atypical PDDs.
- Medical examination results for 15 children with autistic or atypical developmental disorders are detailed.
- Clinically relevant chromosomal, neurological, or biochemical disorders were identified in 8 of the 15 children.
Impact:
- Highlights the significant prevalence of underlying medical conditions in children with autism and atypical PDDs.
- Supports the recommendation for comprehensive medical evaluations in the diagnostic workup of these children.
- Underscores the potential for targeted medical interventions to improve outcomes for affected children.
Abstract:
In children with infantile autism or atypical pervasive developmental disorders somatic aspects play an important role. A review is presented of important hereditary, pre-, peri- and neonatal factors, findings at neurological examination, specific medical disorders and neurochemical and neurophysiological findings. Results of the medical examination of 15 children with autistic or atypical developmental disorders are presented. It is concluded that extensive medical examination of these children is indicated: in 8 out of 15 children a clinically relevant chromosomal, neurological or biochemical disorder could be detected.