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Updated: Apr 17, 2026

Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets
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Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets

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Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive

Peter Hoboth1, Andreas Müller1, Anna Ivanova1

  • 1Molecular Diabetology, Paul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital Carl Gustav Carus and Faculty of Medicine, Technische Universität Dresden, 01307 Dresden, and German Center for Diabetes Research (DZD e.V.), 85764 Neuherberg, Germany;

Proceedings of the National Academy of Sciences of the United States of America
|February 4, 2015
PubMed

Keywords:
Bayesian probability theorydiabetesisletsprocessivitysecretion

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