Related Experiment Video
Updated: Apr 17, 2026

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
Published on: February 7, 2025
Pediatric delirium and associated risk factors: a single-center prospective observational study
Gabrielle Silver1, Chani Traube1, Linda M Gerber1
1Weill Cornell Medical College.
Insights
Pediatric delirium affects 21% of critically ill children. Key risk factors include developmental delay, mechanical ventilation, and young age. Further research is needed to understand this condition.
Area of Science:
- Pediatric Critical Care Medicine
- Child Psychiatry
- Neuroscience
Background:
- Delirium is a common complication in critically ill children.
- Identifying prevalence and risk factors is crucial for timely intervention.
- The Cornell Assessment of Pediatric Delirium (CAP-D) is a validated screening tool.
Purpose of the Study:
- To determine the prevalence of delirium in critically ill children at a single institution.
- To identify risk factors associated with delirium in this population.
- To inform future research and clinical practice.
Main Methods:
- Prospective observational pilot study.
- Secondary analysis of data from CAP-D validation.
- Psychiatric evaluation using Diagnostic and Statistical Manual IV criteria.
- Study conducted in a pediatric intensive care unit (PICU).
Main Results:
- Delirium prevalence was 21% in the studied sample.
- Identified risk factors: developmental delay, mechanical ventilation, age 2-5 years.
- Multivariate analysis confirmed these associations.
Conclusions:
- Pediatric delirium is prevalent in critically ill children.
- Specific risk factors are identifiable.
- Further multi-institutional studies are needed to explore prevalence, modifiable factors, interventions, and outcomes.
Objective:
To describe a single-institution pilot study regarding prevalence and risk factors for delirium in critically ill children.
Design:
A prospective observational study, with secondary analysis of data collected during the validation of a pediatric delirium screening tool, the Cornell Assessment of Pediatric Delirium.
Setting:
This study took place in the PICU at an urban academic medical center.
Patients:
Ninety-nine consecutive patients, ages newborn to 21 years.
Intervention:
Subjects underwent a psychiatric evaluation for delirium based on the Diagnostic and Statistical Manual IV criteria.
Measurements And Main Results:
Prevalence of delirium in this sample was 21%. In multivariate analysis, risk factors associated with the diagnosis of delirium were presence of developmental delay, need for mechanical ventilation, and age 2-5 years.
Conclusions:
In our institution, pediatric delirium is a prevalent problem, with identifiable risk factors. Further large-scale prospective studies are required to explore multi-institutional prevalence, modifiable risk factors, therapeutic interventions, and effect on long-term outcomes.
More Related Videos
Related Concept Videos
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacokinetics in Pediatric Patients: Drug Excretion
Parkinson Disease l: Introduction
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

