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A new aromatic glucoside from stem bark of Illicium difengpi K.I.B. et K.I.M
Chuntong Li1, Zhijun Wu, Wansheng Chen
1a Department of Pharmacy and Pharmacology , First Affiliated Hospital of PLA General Hospital , Beijing 100048 , P.R. China.
Natural Product Research
|February 4, 2015
Abstract:
A new aromatic glucoside, namely 4-methoxyphenyl-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside (1), together with six known aromatic glucosides (2-7) were isolated from the stem bark of Illicium difengpi. The structures of these compounds were established by spectroscopic methods. The isolated aromatic glucosides were tested for anti-inflammatory activity. Compounds 1, 3 and 6 showed significant inhibitory effect on nuclear factor kappa B (NF-κB) in RAW 264.7 macrophages induced by lipopolysaccharide.