Three cases of Bartonella quintana infection in children

Andrea Magnolato1, Federica Pederiva, Giulia Spagnut

  • 1*University of Trieste, Trieste, Italy; †Department of Pediatrics, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo," Trieste, Italy; and ‡Department of Pediatrics, Udine University Hospital, Udine, Italy.

Insights

Bartonella quintana infection, though rare, should be considered in children with persistent fever and swollen lymph nodes unresponsive to standard antibiotics. Prompt diagnosis and treatment led to complete recovery in all observed pediatric cases.

Area of Science:

  • Infectious Diseases
  • Pediatrics
  • Bacteriology

Background:

  • Bartonella quintana is an emerging infectious agent.
  • Diagnosis of B. quintana infection can be challenging, especially in pediatric populations.
  • Unexplained fever and lymphadenopathy warrant consideration of atypical pathogens.

Observation:

  • Three pediatric cases of Bartonella quintana infection were treated at IRCCS Burlo Garofolo, Trieste.
  • Patient presentation included fever and lymphadenopathy.
  • Symptoms persisted despite conventional antibiotic therapies.

Findings:

  • All three children diagnosed with Bartonella quintana infection achieved complete clinical recovery.
  • No sequelae or relapses were observed post-treatment.
  • This suggests effective therapeutic strategies for pediatric B. quintana infections.

Implications:

  • Highlights the importance of considering B. quintana in the differential diagnosis of pediatric febrile illnesses.
  • Emphasizes the need for timely and appropriate antimicrobial treatment for favorable outcomes.
  • Contributes to understanding the clinical spectrum and management of Bartonella infections in children.

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