Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Metal-Ligand Bonds02:51

Metal-Ligand Bonds

25.9K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
25.9K
Assembly of Signaling Complexes01:30

Assembly of Signaling Complexes

7.2K
Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
7.2K
Protein Complex Assembly02:41

Protein Complex Assembly

17.3K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
17.3K
Valence Bond Theory02:42

Valence Bond Theory

11.9K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
11.9K
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

1.6K
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
1.6K
Structural Isomerism02:34

Structural Isomerism

22.6K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly,...
22.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinical application of superimposed high-frequency jet ventilation in adult and pediatric laryngotracheal surgery].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2026
Same author

[A case of primary giant malignant melanoma of the eye with extraocular extension].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same author

[Research progress on cardiac L-type calcium channel mutations in Brugada syndrome and early repolarization syndrome].

Zhonghua xin xue guan bing za zhi·2025
Same author

[A retrospective study on an innovative modular surgical technique in laparoscopic total gastrectomy combined with spleen-preserving hilar lymphadenectomy].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery·2025
Same author

[Advances in catheter ablation for patients with atrial fibrillation and heart failure].

Zhonghua nei ke za zhi·2025
Same author

Genome-wide identification of xyloglucan endotransglucosylase/hydrolase genes in almond and PdXTH2 overexpression induces cell structural disassembly and promotes programmed cell death progression.

Plant biology (Stuttgart, Germany)·2025

Related Experiment Video

Updated: Apr 17, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

10.2K

Protein-responsive assemblies from catechol-metal ion supramolecular coordination.

C Yuan1, J Chen, S Yu

  • 1College of Materials, Xiamen University, Xiamen, 361005, China.

Soft Matter
|February 5, 2015
PubMed
Summary

Researchers developed a novel supramolecular strategy using catechol-metal ion coordination and polymer self-assembly to create tunable nanoassemblies. These hybrid structures demonstrate protein-responsive disassembly, offering new possibilities for functional materials.

More Related Videos

Synthesis of a Water-soluble Metal–Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

12.1K
Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

10.0K

Related Experiment Videos

Last Updated: Apr 17, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

10.2K
Synthesis of a Water-soluble Metal–Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

12.1K
Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

10.0K

Area of Science:

  • Supramolecular chemistry
  • Materials science
  • Nanotechnology

Background:

  • Catechol-metal ion coordination is widely used for functional materials like adhesives and hydrogels.
  • Fabricating complex nanoarchitectures without templates is challenging due to uncontrollable crosslinking.
  • Existing methods often require specific ligands or intricate molecular designs.

Purpose of the Study:

  • To develop a versatile supramolecular approach for creating tunable polymer-based nanoarchitectures.
  • To investigate the protein-responsive disassembly of these hybrid nanoassemblies.
  • To overcome limitations in constructing nanoarchitectures using catechol-metal ion coordination.

Main Methods:

  • Combining catechol-metal ion coordination with polymer self-assembly.
  • Utilizing UV/vis absorption and fluorescence quenching/recovery techniques.
  • Investigating the disassembly triggered by protein interactions.

Main Results:

  • Successfully organized polymers into diverse hybrid nanoassemblies (particles, vesicles, Janus vesicles).
  • Demonstrated complete disassembly of assemblies in response to proteins.
  • Confirmed that proteins sequester metal ions, degrading the coordination network.

Conclusions:

  • The combined supramolecular approach enables controlled fabrication of protein-responsive polymer nanoarchitectures.
  • Protein-induced metal ion chelation offers a simple and effective disassembly mechanism.
  • This strategy provides a template-free route to advanced functional nanomaterials.