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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
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The complete mitochondrial genome for an autoimmune thyroiditis mouse strain NOD.H-2h4
Na Xu1, Yin-Xi Ji1, Cong Qiao1
1a Department of Endocrinology , Nanyang Central Hospital of Henan Province , Nanyang , China.
Mitochondrial DNA. Part A, DNA Mapping, Sequencing, and Analysis
|February 5, 2015
Abstract:
Autoimmune thyroiditis is a chronic organ-specific autoimmune disease characterized by mononuclear cell infiltration of the thyroid gland and destruction of thyroid follicles by the infiltrating inflammatory cells. We sequenced the complete mitochondrial genome sequencing of an autoimmune thyroiditis mouse strain NOD.H-2h4 for the first time. The total length of the mitogenome was 16,310 bp and contains 159 SNPs compared with the house mouse reference sequence.

