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Native Valve Endocarditis due to Ralstonia pickettii: A Case Report and Literature Review
Joseph Orme1, Tomas Rivera-Bonilla2, Akil Loli3
1Department of Internal Medicine, Banner Good Samaritan Medical Center, Phoenix, AZ 85006, USA.
Ralstonia pickettii bacteremia is rare, especially in healthy individuals. This case highlights its potential to cause severe aortic valve abscess and complete heart block, a first for this pathogen.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Ralstonia pickettii is an uncommon pathogen, rarely causing infections in healthy individuals.
- Infections due to Ralstonia species are infrequently reported, particularly severe cardiac manifestations.
Purpose of the Study:
- To report a rare case of Ralstonia pickettii bacteremia.
- To describe the development of an aortic valve abscess and complete heart block secondary to R. pickettii infection.
- To document the first known instance of Ralstonia species causing infective endocarditis with a perivalvular abscess.
Main Methods:
- Case report detailing clinical presentation, diagnostic workup, and management.
- Microbiological identification of Ralstonia pickettii from blood cultures.
- Echocardiographic and imaging studies to assess cardiac involvement and abscess formation.
Main Results:
- The patient presented with bacteremia caused by Ralstonia pickettii.
- The infection progressed to an aortic valve abscess.
- Complete heart block developed as a complication of the aortic valve abscess.
- This represents the first reported case of Ralstonia species causing infective endocarditis with a perivalvular abscess.
Conclusions:
- Ralstonia pickettii can cause severe invasive infections, including infective endocarditis with abscess formation.
- Infective endocarditis due to R. pickettii can lead to significant cardiac complications such as complete heart block.
- This case underscores the importance of considering rare pathogens in the differential diagnosis of severe infections, especially in immunocompromised or critically ill patients.
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