Related Experiment Video
Updated: Apr 17, 2026

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
Published on: March 9, 2018
Detection of bromine by ICP-oa-ToF-MS following photochemical vapor generation
1National Research Council of Canada, Measurement Science and Standards , Ottawa, Ontario K1A 0R6, Canada.
Abstract:
A unique flow-through photochemical reactor is utilized for the generation of volatile methyl bromide from aqueous solutions of bromide and bromate ions in a medium of 2% acetic acid containing 3000 μg/mL NH4Cl. The volatile product is transported to a thin-film gas-liquid phase separator and directed to an inductively coupled plasma (ICP) tine-of-flight mass spectrometer for detection and quantitation using either of the (79)Br or (81)Br isotopes. Utilizing a sample flow rate of 3.3 mL/min and a 13 s irradiation time, a detection limit of 0.14 ng/mL is achieved, yielding a 17-fold enhancement over conventional solution nebulization. The estimated generation efficiency of 95% provides for a significant increase in analyte transport efficiency to the ICP. Precision of replicate measurement is 2.5% (RSD) at 20 ng/mL. The methodology was validated by successful determination of bromine in reference materials, including IRMM (BCR-611) low level bromide in groundwater, NIST SRM 1568b Rice Flour, and SRM 1632 bituminous coal.
More Related Videos
07:57Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
Published on: July 25, 2014
05:48Analysis of Volatile and Oxidation Sensitive Compounds Using a Cold Inlet System and Electron Impact Mass Spectrometry
Published on: September 5, 2014
Related Concept Videos
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview
Gas Chromatography: Types of Detectors-II
Inductively Coupled Plasma Atomic Emission Spectroscopy: Principle
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences
Atomic Emission Spectroscopy: Lab
Gas Chromatography: Types of Detectors-I
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...