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Updated: Apr 17, 2026

Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Benign (BI-RADS 2) lesions in breast MRI
C Spick1, D H M Szolar2, M Tillich2
1Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna (AKH), Waehringer-Guertel 18-20, 1090 Vienna, Austria.
Malignancy is never found in breast lesions categorized as Breast Imaging-Reporting and Data System (BI-RADS) 2 on MRI scans. Therefore, biopsies are not needed for these benign-appearing findings.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Breast MRI is a crucial tool for breast cancer detection.
- The Breast Imaging-Reporting and Data System (BI-RADS) categorizes findings to standardize reporting.
- BI-RADS 2 indicates benign findings, but malignancy assessment is essential.
Purpose of the Study:
- To determine the frequency of malignancy in breast lesions classified as BI-RADS 2 on MRI.
- To evaluate the necessity of biopsies for BI-RADS 2 lesions.
Main Methods:
- Retrospective analysis of 192 breast lesions classified as BI-RADS 2 on MRI.
- Lesions were assessed via histopathology or a minimum 2-year imaging/clinical follow-up.
- Data from 1265 consecutive patients undergoing breast MRI were reviewed.
Main Results:
- None of the 192 BI-RADS 2 lesions were malignant (0%).
- Histopathology confirmed benign findings in 34.9% of lesions.
- The remaining 65.1% showed no changes during follow-up, indicating benignancy.
Conclusions:
- Breast lesions classified as BI-RADS 2 on MRI have a zero frequency of malignancy.
- Biopsies are unnecessary for BI-RADS 2 breast lesions, simplifying patient management.
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