Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neurulation

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A retinoid acid 'resistant' t(15;17) acute promyelocytic leukemia cell line: isolation, morphological, immunological, and molecular features.

Leukemia·1992

Same author

Tumor-associated karyotypic lesions coselected with in vitro macrophage differentiation.

Genes, chromosomes & cancer·1992

Same author

A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma.

The EMBO journal·1992

Same author

Relapse as acute monoblastic leukemia (AML-M5) of t(6;9) acute myeloblastic leukemia (AML-M2).

Leukemia·1992

Same author

Abnormalities of chromosome 18 in myelodysplastic syndromes and secondary leukemia.

Cancer genetics and cytogenetics·1992

Same author

Effects of yohimbine on heart rate variability in panic disorder patients and normal controls: a study of power spectral analysis of heart rate.

Journal of cardiovascular pharmacology·1992

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Neuroprotection in preterm infants.

R Berger¹, S Söder¹

¹Marienhaus Klinikum St. Elisabeth, Department of Obstetrics and Gynecology, 56564 Neuwied, Germany.

Biomed Research International

|February 5, 2015

Summary

Preventing preterm birth and brain damage in infants is crucial. Interventions like magnesium sulfate, delayed cord clamping, and potential stem cell therapies show promise for protecting the developing brain.

Area of Science:

Neonatal neurology
Perinatal medicine
Neuroprotection

Background:

Preterm infants (before 30 weeks) face high risks of perinatal brain damage from cerebral ischemia or intrauterine infection.
Early prevention of preterm birth and infection is key to reducing cerebral injury.
The abrupt removal of maternal estradiol and progesterone in preterm infants may leave their brains vulnerable.

Purpose of the Study:

To review current and emerging strategies for preventing perinatal brain damage in preterm infants.
To highlight the neuroprotective potential of various interventions.

Main Methods:

Review of existing literature on interventions for preterm infants.
Analysis of studies on magnesium sulfate, delayed umbilical cord clamping, mesenchymal stem cells, and hormone therapy.

More Related Videos

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

Published on: May 16, 2015

Preterm EEG: A Multimodal Neurophysiological Protocol

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

Related Experiment Videos

Last Updated: Apr 17, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

Published on: May 16, 2015

Preterm EEG: A Multimodal Neurophysiological Protocol

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

Main Results:

Intravenous magnesium sulfate significantly reduces cerebral palsy and motor dysfunction.
Delayed umbilical cord clamping decreases brain hemorrhage rates by up to 50%.
Mesenchymal stem cells show neuroprotective potential in animal models, promoting brain regeneration.

Conclusions:

Magnesium sulfate and delayed cord clamping are effective preventative measures.
Mesenchymal stem cells hold promise for future clinical application.
Estradiol and progesterone neuroprotection requires further clinical investigation.