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Updated: Apr 17, 2026
06:07
Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
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Association between smoking and hand dermatitis--a systematic review and meta-analysis
J Lukács1, S Schliemann1, P Elsner1
1Department of Dermatology, University Hospital Jena, Jena, Germany.
Summary
This study found no significant link between tobacco smoking and developing hand dermatitis. However, smoking might still worsen existing hand dermatitis cases.
Area of Science:
- Dermatology
- Epidemiology
- Public Health
Background:
- Tobacco smoking is a known factor influencing inflammatory skin conditions.
- The relationship between smoking and hand dermatitis requires further investigation.
Purpose of the Study:
- To systematically review and meta-analyze the association between tobacco smoking and hand dermatitis.
- To determine if smoking is a risk factor for developing hand dermatitis.
Main Methods:
- Systematic review and meta-analysis of studies published between 1980 and 2013.
- Searched MEDLINE, Embase, and Cochrane Central Register databases.
- Included one cohort and two cross-sectional studies involving 4,113 cases and 34,875 controls.
Main Results:
- The meta-analysis did not confirm a significant association between smoking and hand dermatitis (OR 0.99; 95% CI 0.88-1.11).
- High heterogeneity (I² = 72%) was observed across the included studies.
- One study reported a significant association, but this was not supported by the overall meta-analysis.
Conclusions:
- Tobacco smoking is not identified as a significant risk factor for developing hand dermatitis based on this meta-analysis.
- Results are heavily influenced by two large studies from a single country.
- Smoking's potential to negatively influence the course or severity of existing hand dermatitis cannot be excluded.
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