Stent dislodgement induced by a vasodilator used for severe coronary artery spasm caused by Kounis syndrome

Masahiro Nishi1, Kan Zen2, Daisuke Kambayashi2

  • 1Department of Cardiology, Omihachiman Community Medical Center, Tsuchidacho 1379, Omihachiman, Shiga, Japan. mhiro_nishi@yahoo.co.jp.

Insights

A rare complication of percutaneous coronary intervention, coronary stent dislodgement, was successfully treated. Vasodilators used for Kounis syndrome-induced coronary artery spasm caused the dislodged stent.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Device Complications

Background:

  • Percutaneous coronary intervention (PCI) is a common procedure for treating coronary artery disease.
  • Coronary stent dislodgement is a rare but serious complication following PCI.
  • Kounis syndrome, characterized by acute coronary syndrome and mast cell activation, can cause severe coronary artery spasm.

Observation:

  • A case of extracoronary stent dislodgement is presented.
  • The dislodgement occurred after administration of a vasodilator to manage severe coronary artery spasm.
  • The spasm was attributed to Kounis syndrome.

Findings:

  • Successful retrieval of the extracoronary dislodged stent was achieved.
  • The vasodilator, intended to treat coronary spasm, inadvertently triggered stent dislodgement.
  • This highlights a unique mechanism of stent dislodgement in the context of Kounis syndrome.

Implications:

  • Successful stent retrieval avoids major adverse cardiac events, such as stent embolization or the need for emergency surgery.
  • Understanding this complication can inform clinical practice regarding vasodilator use in patients with Kounis syndrome and PCI.
  • This case expands the known spectrum of stent dislodgement etiologies.

Related Concept Videos

Antihypertensive Drugs: Vasodilators01:23

Antihypertensive Drugs: Vasodilators

Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as minoxidil and hydralazine primarily target arteries and arterioles, while sodium nitroprusside acts on arterioles and venules. Minoxidil, functioning as a prodrug, is metabolized by hepatic sulfotransferase into its active form, minoxidil sulfate, after oral administration. This metabolite binds to the sulfonylurea receptor (SUR) component of...
2.5K
Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
5.1K
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.8K
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
626
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
667
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.6K