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Neuroleptic-valproic acid combination in treatment of psychotic symptoms: a three-case report
A Wassef1, D J Watson, P Morrison
1Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77550.
Journal of Clinical Psychopharmacology
|February 1, 1989
Abstract:
Valproic acid is infrequently used for treatment of psychosis. Three consecutive patients with severe neuroleptic-resistant psychotic symptoms responded dramatically to the combination of valproic acid and neuroleptics. All three had normal EEGs and CT scans. Outpatient follow-up showed that the combination was effective in maintaining remissions.