Diffuse large B - Cell lymphoma involving the maxilla in a minor

Area of Science:

• Oncology
• Hematology
• Oral Pathology

Background:

• Lymphomas are malignant neoplasms originating from lymphocytes.
• Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
• Primary oral cavity lymphomas in pediatric patients are uncommon.

Observation:

• An 11-year-old male presented with maxillary labial mucosal swelling and oral candidiasis.
• Clinical presentation suggested an infectious or inflammatory process.
• Diagnostic workup included biopsy and immunohistochemistry.

Findings:

• Biopsy confirmed diffuse large B-cell lymphoma (DLBCL) of the maxilla.
• Immunohistochemistry was crucial for definitive diagnosis.
• This represents a rare case of primary oral DLBCL in a minor.

Implications:

• Highlights the importance of considering rare diagnoses in pediatric oral pathology.
• Contributes to the limited literature on primary oral DLBCL in children.
• Emphasizes the role of prompt biopsy and immunohistochemistry for accurate diagnosis and management.