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Maspin as a tumour suppressor in salivary gland tumour
Bassel Tarakji1, Nipun Ashok1, Mohammad Kinan Sheirawan2
1Faculty, Department of Oral Maxillofacial Sciences, Al-Farabi College of Dentistry and Nursing , Riyadh .
Abstract:
Maspin is a protein that belongs to serin protease inhibitor (serpin) superfamily. The purpose of this study was to review the literature concerning the expression of maspin in salivary gland tumours. A literature search was done using MEDLINE, accessed via the National Library of Medicine PubMed interface. Statistical analysis was not done because only seven studies were available in literature, the collected data were different and the results could not be compared. Expression of maspin was down regulated in more aggressive salivary gland tumours. Maspin may function as a tumour suppressor in salivary gland tumours.
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