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[Endoscopic purse-string suture for the gastric wall defect after full-thickness resection]
Yin Zhang1, Zhining Fan, Jie Wu
1Department of Digestive Endoscopy, The First Affiliated Hospital of Nanjing Medical University(Jiangsu Province Hospital), Nanjing 210029, China. wxnanjing@163.com.
Summary
Endoscopic purse-string suture (EPSS) effectively closes gastric wall defects after tumor resection. This safe and efficient endoscopic technique ensures successful healing with no major complications.
Area of Science:
- Gastroenterology
- Surgical Endoscopy
- Oncology
Background:
- Gastric wall defects can occur after endoscopic resections for tumors.
- Effective closure of these defects is crucial for patient recovery and preventing complications.
Purpose of the Study:
- To evaluate the efficacy and safety of endoscopic purse-string suture (EPSS) using metallic clips and endoloop.
- To assess EPSS for closing gastric wall defects following tumor resection.
Main Methods:
- Retrospective analysis of 25 patients with gastric tumors (adenocarcinoma and GIST) who underwent EPSS.
- EPSS was performed for perforations after endoscopic submucosal dissection (ESD) or full-thickness resection.
Main Results:
- Successful EPSS in all 25 patients with no severe complications.
- Average procedure time was 49.8 minutes; negative resection margins achieved.
- Patients experienced short recovery times, with lesions healed by one-month follow-up.
Conclusions:
- Endoscopic purse-string suture (EPSS) with metallic clips and endoloop is a safe and effective method.
- EPSS successfully closes gastric wall defects after full-thickness resection, promoting healing.

