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Evolution. Comment on "A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity".

Jacob O Brunkard1, Anne M Runkel1, Patricia C Zambryski2

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Researchers challenge a new model of transcription factor evolution, demonstrating that LEAFY genes evolve through duplication. Evidence from moss species with multiple LEAFY orthologs supports this evolutionary pathway.

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Area of Science:

  • Evolutionary biology
  • Plant genetics
  • Molecular evolution

Background:

  • A recent model proposed transcription factor evolution, exemplified by LEAFY, occurs without gene duplication.
  • This model contradicts established plant evolutionary history and existing evidence.

Purpose of the Study:

  • To contest the proposed model of transcription factor evolution.
  • To provide evidence supporting the role of gene duplication in LEAFY evolution.

Main Methods:

  • Analysis of a dataset including moss species.
  • Identification and comparison of LEAFY orthologs across species.

Main Results:

  • A moss species within the dataset was found to possess multiple LEAFY orthologs.
  • This finding directly contradicts the model of evolution without gene duplication.

Conclusions:

  • The evolution of LEAFY, a key plant transcription factor, involves gene duplication.
  • The proposed model by Sayou et al. is inconsistent with observed evolutionary patterns in plants.