Tissue specific differences in the fatty acid composition of the marmoset monkey (Callithrix jacchus)

1. The possible relationship between the fatty acid composition of the adipose tissue of the marmoset monkey (Callithrix jacchus) and its dietary lipid intake was examined after a long-term feeding trial. 2. Only the proportions of stearic and linoleic acid in the adipose tissue were similar to those in the diet. The proportions of all other saturated and unsaturated fatty acid components were significantly different thus greatly reducing the potential value of this relationship in the marmoset. 3. The phospholipid fatty acid profiles of cardiac and skeletal muscle, aortae, kidney, liver, lung and brain were also compared to those of the plasma, platelets or red blood cells. 4. With the exception of the liver where the fatty acid profile is similar to that of the plasma, no clear relationships were found between the fatty acid profiles of these tissues and the components of the blood. 5. The fatty acid composition of skeletal muscle was very similar to that of the cardiac muscle of the marmoset, suggesting that muscle biopsy might be useful as an index of cardiac muscle composition.