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High frequency oscillatory ventilation in children. What do we know so far?
1Critical Care Division, Department of Pediatrics, University of Alabama at Birmingham Birmingham, AL, USA - francodiazr@gmail.com.
Insights
High frequency oscillatory ventilation (HFOV) offers potential benefits for pediatric respiratory failure, aiming to improve gas exchange and limit lung injury. This review explores HFOV principles and its application in critical pediatric respiratory conditions.
Area of Science:
- Pediatric Critical Care Medicine
- Respiratory Physiology
- Mechanical Ventilation
Background:
- Pediatric respiratory failure is a common reason for ICU admission globally.
- Acute respiratory distress syndrome (ARDS) is the most severe form, with high mortality (33%).
- Current ventilator strategies for heterogeneous ARDS have limitations.
Purpose of the Study:
- To review the principles and physiology of High Frequency Oscillatory Ventilation (HFOV).
- To discuss the role of HFOV in managing pediatric respiratory failure.
- To highlight HFOV strategies like "open lung" and "low volume" ventilation.
Main Methods:
- Review of existing literature on HFOV in pediatric respiratory failure.
- Discussion of physiological principles underlying HFOV.
- Analysis of HFOV application in specific pediatric conditions.
Main Results:
- HFOV is an alternative mechanical ventilation strategy with potential to improve gas exchange.
- HFOV may help limit ventilator-induced lung injury.
- Specific strategies like "open lung" and "low volume" ventilation are discussed for different pediatric respiratory failure scenarios.
Conclusions:
- HFOV presents an alternative approach for pediatric respiratory failure management.
- The "open lung" strategy is emphasized for conditions reducing functional residual capacity.
- The "low volume" strategy is relevant for airleak syndromes like pneumothorax.
Abstract:
Respiratory failure in children continues to be a common and important indication for admission to intensive care units around the world. Acute respiratory distress syndrome represents the most severe form of respiratory failure in children and results from a variety of pulmonary and extra-pulmonary conditions. Despite important strides in our understanding and improved ventilator strategies of this very heterogeneous disease process, the mortality continues to be fairly high at 33%. High frequency oscillatory ventilation is an alternative form of mechanical ventilation with some attractive features in respect to attempting to improve gas exchange limiting ventilator induced lung injury. The objective of this review is to discuss the principles and the physiology of high frequency oscillatory ventilation, and its role in the management of children with respiratory failure. The adult literature will briefly be reviewed. The main emphasis on this review will be on the use of the "open lung" strategy in conditions that cause a reduction in functional residual capacity. In addition the "low volume" strategy that is useful in the setting of airleaks, such as pneumothorax and pneumomediastinum, will be briefly discussed.
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