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[Genes for extreme violent behaviour?].

Bertrand Jordan1

  • 1UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d'adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France - CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 09, France.

Medecine Sciences : M/S
|February 7, 2015
PubMed
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Genetic variants linked to extreme violence were identified in criminals. Low activity alleles of monoamine oxidase A (MAOA) and the CD13 gene show associations, but these common alleles indicate risk, not causation.

Area of Science:

  • Behavioral genetics
  • Neuroscience
  • Forensic psychology

Context:

  • Understanding the genetic underpinnings of criminal behavior is crucial for developing targeted interventions.
  • Previous research has explored various genetic factors associated with aggression and violence.

Purpose:

  • To investigate the association between specific genetic variations and the degree of violent behavior in a criminal population.
  • To identify potential genetic markers for extreme violent tendencies using candidate gene and genome-wide association study (GWAS) approaches.

Summary:

  • A genetic study identified statistically significant associations between extreme violent behavior and low-activity alleles of monoamine oxidase A (MAOA) and the CD13 gene in criminals.
  • Both candidate gene and GWAS methods were employed to analyze genetic data.

Related Experiment Videos

  • The implicated alleles, while associated with risk, are common in the general population and thus not directly causal.

    • Impact:

    • Findings suggest that certain common genetic variations may serve as indicators of increased risk for extreme violence.
    • This research contributes to the complex interplay between genetics and criminal behavior, informing future etiological and forensic studies.
    • Highlights the need for cautious interpretation of genetic findings in relation to complex behaviors like violence.