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Updated: Apr 17, 2026

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Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins
Published on: August 7, 2014
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Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine
Megan Twomey1, Tereza Vokatá, Manian Rajesh Kumar
1Biomolecular Sciences Institute, Department of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA. jmoon@fiu.edu.
Abstract:
Four different conjugated polymer nanoparticles (CPNs) were used to differentiate structurally similar glycosaminoglycans (GAGs) in a urine simulant. Unique emission response patterns of CPNs were analyzed by linear discriminant analysis (LDA), confirming that structurally diverse CPNs are sensitive and effective at differentiating GAGs in a complex biological medium.

