Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep and durable prostate-specific antigen response following comprehensive involved site radiotherapy for prostate cancer oligometastases.

Urologic oncology·2026
Same author

Validation of the 2025 IMS/IMWG risk classification in patients with newly diagnosed multiple myeloma treated with quadruplets and autologous stem cell transplant.

British journal of haematology·2026
Same author

Quantitative bias analyses to address measurement error in time-to-event endpoints.

American journal of epidemiology·2026
Same author

Distinct trajectory of measurable residual disease in t(11;14) myeloma treated with quadruplet therapy.

Blood·2026
Same author

PET Imaging of CD38 and IND enabling studies of [<sup>89</sup>Zr]Zr-DFO-Isatuximab.

Molecular imaging and biology·2025
Same author

Reversing the sequence: Efficacy of BCMA-directed therapy following progression on GPRC5D-directed therapies in relapsed multiple myeloma.

British journal of haematology·2025
Same journal

LINC01234 Coordinates Protein Interactions and ceRNA Networks to Enhance YWHAZ-Driven Malignancy in Triple-Negative Breast Cancer.

Clinical breast cancer·2026
Same journal

The Clinical Impact of Not Performing Axillary Lymph Node Dissection in pN+sn Breast Cancer Patients Undergoing Total Mastectomy.

Clinical breast cancer·2026
Same journal

Reducing Clip Migration in Mammographic-Guided Vacuum Assisted Biopsy With Direct Insertion of the UltraCor Twirl Clip Marker: A Quality Improvement Project.

Clinical breast cancer·2026
Same journal

Tracking Utilization of Neoadjuvant Endocrine Therapy (NET) and Neoadjuvant Chemotherapy (NCT) for Hormone Receptor-Positive Breast Cancer (HR + BC) in the U.S.A. Over Time - A TriNetX Database Study.

Clinical breast cancer·2026
Same journal

A Study on the Association Between Preventive Behaviors and Quality of Life in High-risk Populations for Postoperative Lymphedema Following Breast Cancer Surgery.

Clinical breast cancer·2026
Same journal

Prevalence and Prognostic Implications of Circulating Tumor Cells Among Patients Undergoing Neoadjuvant Chemotherapy for Early-Stage Breast Cancer.

Clinical breast cancer·2026
See all related articles

Related Experiment Video

Updated: Apr 17, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.8K

Grade and Prognosis in Localized Primary Angiosarcoma.

Manjari Pandey1, Gregory R Sutton1, Smith Giri2

  • 1Department of Medical Oncology, West Cancer Center/ University of Tennessee Health Science Center, Memphis, TN.

Clinical Breast Cancer
|February 10, 2015
PubMed
Summary
This summary is machine-generated.

Histologic grade significantly impacts survival for localized primary breast angiosarcoma (PAOB). Adjuvant radiation therapy does not improve outcomes for localized PAOB, irrespective of tumor grade.

Keywords:
AngiosarcomaHistologic gradeRadiation therapySEER

More Related Videos

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

3.4K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

1.0K

Related Experiment Videos

Last Updated: Apr 17, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.8K
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

3.4K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

1.0K

Area of Science:

  • Oncology
  • Surgical Pathology
  • Cancer Research

Background:

  • Primary angiosarcoma of the breast (PAOB) is a rare malignancy.
  • Existing data on the prognostic impact of tumor grade in PAOB is conflicting.

Purpose of the Study:

  • To investigate the prognostic significance of histologic grade on survival outcomes in patients diagnosed with primary angiosarcoma of the breast.
  • To evaluate the efficacy of adjuvant radiation therapy in localized PAOB.

Main Methods:

  • Utilized the Surveillance, Epidemiology, and End Results (SEER) 18 database (1973-2010) to identify patients with PAOB.
  • Conducted survival analyses using SEER*Stat, Microsoft Excel, and GraphPad Prism.
  • Employed Fisher exact test and log rank (Mantel-Cox) tests for statistical comparisons.

Main Results:

  • A total of 226 women with PAOB were analyzed; 72% had localized disease.
  • Histologic grade was a significant predictor of overall survival (OS) for localized PAOB (P < .001).
  • Median OS for localized Grade 1 and 2 disease was not reached, compared to 36 months for Grade 3 disease.
  • Adjuvant radiation therapy did not demonstrate a survival benefit for localized PAOB across all grades (P = .676 for low/intermediate grades, P = .589 for high grade).

Conclusions:

  • Histologic grade is a critical prognostic factor for localized primary angiosarcoma of the breast.
  • Adjuvant radiation therapy does not improve survival in patients with localized PAOB, regardless of tumor grade.