Related Experiment Video
Updated: Apr 17, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
Economic evaluations of contingency management in illicit drug misuse programmes: A systematic review
James Shearer1, Hiong Tie, Sarah Byford
1Centre for the Economics of Mental and Physical Health, Institute of Psychiatry, King's College London, London, UK.
Insights
Contingency management (CM) shows clinical effectiveness for opiate substitution therapy but lacks clear cost-effectiveness evidence. More research is needed to determine if CM is a viable option for national health systems.
Area of Science:
- Health Economics
- Addiction Treatment
- Clinical Guidelines
Background:
- UK clinical guidelines from 2007 recommended contingency management (CM) as an adjunct to opiate substitution therapy.
- Despite documented clinical effectiveness, CM has not been widely adopted in the UK.
- Evidence regarding the cost-effectiveness of CM is less clear, hindering its adoption by national health systems.
Purpose of the Study:
- To systematically review and synthesize published economic evaluations of contingency management (CM).
- To assess the cost-effectiveness of CM as an adjunct to opiate substitution therapy.
- To identify gaps in the evidence base for CM's cost-effectiveness.
Main Methods:
- Systematic review of published economic evaluations.
- Descriptive synthesis of findings from identified studies.
- Analysis of studies conducted in US treatment settings.
Main Results:
- Nine economic evaluations were identified, primarily from US settings.
- All studies indicated that CM increased both costs and effects (e.g., drug abstinence, medication adherence).
- The existing evidence base has limited generalizability beyond specific research settings and populations.
Conclusions:
- The current evidence on the cost-effectiveness of CM is insufficient for definitive conclusions.
- More comprehensive and relevant evidence is required to support the adoption of CM by health systems.
- Further research is needed to establish the cost-effectiveness of CM in diverse populations and settings.
Issues:
UK clinical guidelines published in 2007 recommended contingency management (CM) as an adjunct to opiate substitution therapy. However, CM has not been adopted in the UK despite evidence of clinical effectiveness. Evidence for the cost-effectiveness of CM is less clear and will need to be explored if CM is to be adopted by national health systems in countries such as the UK.
Approach:
Systematic review and descriptive synthesis of published economic evaluations.
Key Findings:
The review identified nine published studies that could be classified as economic evaluations. These were all based within US treatment settings, and five were conducted by the same group of authors. All studies found that the addition of CM to usual care increased both costs and effects (commonly drug abstinence or medication adherence).
Implications:
This review confirms that the existing evidence base for cost-effectiveness has limited generalisability beyond the original research clinical settings and populations.
Conclusion:
The data were not sufficiently strong to make any conclusion about the cost-effectiveness of CM. More relevant and comprehensive evidence for cost-effectiveness than currently exists is needed.
Related Concept Videos
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Behavior Modification
A real-world application of operant conditioning principles is applied...
Drug Dependence
Drug Control Governance: Regulatory Bodies and Their Impact
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...

