Related Experiment Video
Updated: Apr 17, 2026
05:10
Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
10.3K
"Omics" in pharmaceutical research: overview, applications, challenges, and future perspectives.
Shi-Kai Yan1, Run-Hui Liu2, Hui-Zi Jin1
1School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Chinese Journal of Natural Medicines
|February 10, 2015
Summary
Omics technologies like genomics and proteomics offer new biological insights. This review covers their advances, pharmaceutical applications, and future challenges in data analysis.
Area of Science:
- Biological Sciences
- Bioinformatics
- Pharmaceutical Research
Background:
- The post-genomic era is defined by diverse "omics" technologies.
- These technologies enable global biological sample analysis.
- High-throughput approaches and bioinformatics are central to omics.
Purpose of the Study:
- Review the development and advances in omics technologies.
- Summarize omics applications in pharmaceutical research.
- Discuss limitations and future challenges of omics.
Main Methods:
- Review of genomics, transcriptomics, proteomics, and metabolomics.
- Summary of omics applications in drug discovery, toxicity, personalized medicine, and TCM.
- Discussion of multi-omics data processing and dynamic analysis.
Main Results:
- Significant progress in genomics, transcriptomics, proteomics, and metabolomics.
- Established applications of omics in pharmaceutical research.
- Identified limitations and future research directions.
Conclusions:
- Omics technologies have revolutionized biological studies.
- Continued advancements are crucial for pharmaceutical innovation.
- Addressing multi-omics data challenges is key for future prospects.
Related Concept Videos
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
580
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
580
01:26Drug Discovery: Overview
13.6K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
13.6K
01:29Pharmacogenetics and Pharmacogenomics: Overview
202
Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...
202
01:28Biopharmaceutics and Pharmacokinetics: Overview
5.2K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
5.2K
01:29Issues And Trends In Healthcare Delivery System
6.5K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.5K
01:29Pharmacogenomics: Identification of New Drug Targets
98
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
98