Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

582
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
582
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

611
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
611
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

742
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
742
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

521
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
521
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

502
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
502
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

1.2K
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antiphospholipid Antibodies and Atrial Fibrillation: Clinical Implications and the TaPL AF Study Design.

Thrombosis and haemostasis·2026
Same author

Association of Obesity With Mortality and Bleeding in Cancer-Associated Venous Thromboembolism.

Mayo Clinic proceedings·2026
Same author

Intermediate-dose anticoagulation in COVID-19: closing the loop on a long-settled question.

Journal of thrombosis and haemostasis : JTH·2026
Same author

A simple score to identify the sickest normotensive patients with acute pulmonary embolism.

ERJ open research·2026
Same author

Pulmonary embolism epidemiology: trends, risk factors, comorbidities, and clinical implications.

European heart journal·2026
Same author

Development and external validation of an international score to predict cancer 1 year after venous thromboembolism.

European journal of internal medicine·2026

Related Experiment Video

Updated: Apr 17, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
07:59

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

Published on: July 28, 2018

11.9K

Intravenous fluids in acute decompensated heart failure.

Behnood Bikdeli1, Kelly M Strait2, Kumar Dharmarajan3

  • 1Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.

JACC. Heart Failure
|February 10, 2015
PubMed
Summary

Early intravenous fluid administration in acute decompensated heart failure (HF) patients receiving diuretics is common and varies by hospital. This practice is linked to worse patient outcomes, including increased mortality.

Keywords:
diureticsheart failureintravenous fluids

More Related Videos

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.7K
Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis
07:17

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis

Published on: August 17, 2022

3.7K

Related Experiment Videos

Last Updated: Apr 17, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
07:59

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

Published on: July 28, 2018

11.9K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.7K
Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis
07:17

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis

Published on: August 17, 2022

3.7K

Area of Science:

  • Cardiology
  • Hospital Medicine
  • Critical Care Medicine

Background:

  • Intravenous fluids are a common intervention for hospitalized patients.
  • The early use of intravenous fluids in acute decompensated heart failure (ADHF) patients treated with diuretics is not well-characterized.

Purpose of the Study:

  • To determine the utilization of intravenous fluids in the early management of ADHF patients receiving loop diuretics.
  • To assess the association between early intravenous fluid administration and in-hospital adverse outcomes.

Main Methods:

  • Retrospective cohort study of 131,430 hospitalizations for ADHF across 346 hospitals (2009-2010).
  • Assessed intravenous fluid use within the first 2 days of hospitalization.
  • Analyzed variations in fluid administration across hospitals and patient groups.

Main Results:

  • 11% of ADHF hospitalizations received intravenous fluids (median 1,000 ml) in the first 2 days.
  • Patients receiving fluids had significantly higher rates of critical care admission, intubation, renal replacement therapy, and hospital death.
  • Wide variation in fluid administration was observed across hospitals (0% to 71%).

Conclusions:

  • Early intravenous fluid administration is prevalent in ADHF patients treated with diuretics and exhibits significant hospital-level variation.
  • This practice is associated with poorer in-hospital outcomes and requires further investigation.