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Updated: Apr 17, 2026

Measuring the Behavioral Effects of Intraocular Scatter
Published on: February 18, 2021
Comparison of forward light scatter estimations using Shack-Hartmann spot patterns and a straylight meter
Pablo Benito Lopez1, Hema Radhakrishnan1, Vincent Nourrit1
1From the University of Manchester (Lopez, Radhakrishnan, Nourrit), Manchester, United Kingdom.
Purpose:
To determine whether an unmodified commercial wavefront aberrometer (irx3) can be used to estimate forward light scattering and how this assessment matches estimations obtained from the C-Quant straylight meter.
Setting:
University of Manchester, Manchester, United Kingdom.
Design:
Prospective comparative study.
Methods:
Measurements obtained with a straylight meter and with Shack-Hartmann spot patterns using a previously reported metric were compared. The method was first validated in a model eye by spraying an aerosol over 4 contact lenses to generate various levels of scattering. Measurements with both methods were subsequently obtained in healthy eyes.
Results:
The study comprised 33 healthy participants (mean age 38.9 years ± 13.1 [SD]). A good correlation was observed between the density of droplets over the contact lenses and the objective scatter value extracted from the hartmanngrams (r = 0.972, P < .05). However, in eyes of subjects, no significant relationship was found between measurements from the straylight meter and the metric derived from the Shack-Hartmann method (r = 0.133, P = .460).
Conclusions:
The hartmanngrams provided a valid objective measurement of the light scatter in a model eye; the measurements in human eyes were not significantly correlated with those of the light scatter meter. The straylight meter assesses large-angle scattering, while the Shack-Hartmann method collates information from a narrow angle around the center of the point-spread function; this could be the reason for the difference in measurements.
Financial Disclosure:
No author has a financial or proprietary interest in any material or method mentioned.
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