Related Experiment Video

Updated: Apr 17, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

9.3K

Prevalence and treatment of "balloon-uncrossable" coronary chronic total occlusions

Siddharth M Patel1, Nagendra R Pokala, Rohan V Menon

  • 1VA North Texas Health Care System, The University of Texas Southwestern Medical Center at Dallas, Division of Cardiology (111A), 4500 S. Lancaster Rd, Dallas, TX 75216 USA. esbrilakis@gmail.com.

The Journal of Invasive Cardiology
|February 10, 2015
PubMed

Insights

Balloon-uncrossable coronary chronic total occlusions (CTOs) affect 6.4% of percutaneous coronary interventions (PCIs). Most cases can be successfully treated using diverse techniques, despite longer procedure times.

Area of Science:

  • Interventional Cardiology
  • Cardiovascular Research
  • Medical Device Technology

Background:

  • Balloon-uncrossable coronary chronic total occlusions (CTOs) are a challenging subset of CTO percutaneous coronary interventions (PCIs).
  • Limited data exists on the frequency and outcomes of these specific CTOs.

Purpose of the Study:

  • To determine the frequency of balloon-uncrossable CTOs in contemporary CTO PCIs.
  • To evaluate the treatment strategies and success rates for balloon-uncrossable CTOs.

Main Methods:

  • Retrospective analysis of 373 consecutive CTO PCIs performed between 2005 and 2013.
  • Identification and characterization of patients with balloon-uncrossable CTOs.
  • Review of techniques used for crossing and treating these lesions.

Main Results:

  • Balloon-uncrossable CTOs were identified in 6.4% of patients.
  • Successful crossing was achieved in 91.7% of balloon-uncrossable CTOs using various techniques (e.g., microcatheter, laser, subintimal crossing).
  • These cases involved longer procedure and fluoroscopy times and higher contrast volumes, but similar complication rates compared to other CTOs.

Conclusions:

  • Balloon-uncrossable CTOs represent a significant minority of CTO PCIs.
  • Effective treatment strategies exist, leading to high success rates.
  • Interventional cardiologists should be prepared to manage these challenging lesions with specialized techniques.
Abstract

More Related Videos

Complete and Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Hemorrhagic Shock06:30

Complete and Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Hemorrhagic Shock

Published on: May 19, 2022

8.4K

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
435
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
626
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
499
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
463
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
455
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
488