Related Experiment Video
Updated: Apr 17, 2026
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
2.8K
Repeat mitral valve repair for haemolysis in children
Olivia Weill1, Marianne Peyre1, Mathieu Vergnat2
1Toulouse University Hospital, M3C, Paediatric Cardiology Unit, Toulouse, France.
Archives of Cardiovascular Diseases
|February 10, 2015
Summary
Severe hemolytic anemia is a rare complication following mitral valve repair in children with congenital heart disease. Redo mitral valve repair successfully resolved hemolysis in all cases, demonstrating iterative repair is feasible.
Area of Science:
- Cardiology
- Pediatric Surgery
- Hematology
Background:
- Severe hemolytic anemia is an infrequent complication after mitral valve repair in pediatric congenital heart disease.
- This study focuses on four children who developed profound hemolytic anemia post-mitral valve repair for severe mitral regurgitation.
Purpose of the Study:
- To describe the occurrence and management of severe hemolytic anemia after mitral valve repair in children with congenital heart disease.
- To highlight the successful outcome of redo mitral valve repair in resolving hemolysis.
Main Methods:
- Retrospective analysis of clinical, echocardiographic, and surgical data from a French surgical center over a 5-year period.
- Inclusion of four pediatric patients who underwent mitral valve repair and subsequently developed severe hemolytic anemia.
Main Results:
- Patients presented with hemolytic anemia 20-75 days post-surgery, requiring blood transfusions.
- Hemolysis was consistently associated with eccentric mitral regurgitation and deemed mechanical in origin.
- All patients underwent successful redo mitral valve repair, leading to the resolution of hemolysis.
Conclusions:
- Severe hemolysis is a rare but significant complication of mitral valve repair in congenital heart disease.
- Redo mitral valve repair is an effective treatment for mechanical hemolysis secondary to mitral regurgitation.
- Iterative mitral valve repair is a viable option even when redo surgery is necessary.
Related Concept Videos
01:26Mitral Stenosis III: Medical Management
488
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
488
01:25Mitral Regurgitation III: Medical Management
627
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
627
01:22Mitral Stenosis I: Introduction
1.6K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.6K
01:20Mitral Regurgitation I: Introduction
1.2K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.2K
01:28Mitral Regurgitation IV: Nursing Management
557
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
557
01:27Mitral Valve Prolapse I: Introduction
1.0K
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
1.0K