Jove
Visualize
Contact Us

Related Experiment Videos

Racial differences in mole proneness.

F H Rampen1, P E de Wit

  • 1Department of Dermatology, Sint Anna Hospital, Oss, The Netherlands.

Acta Dermato-Venereologica
|January 1, 1989
PubMed
Summary

Racial background significantly influences mole development. White children and adults exhibit higher counts of naevocytic naevi compared to non-white individuals, indicating a genetic predisposition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Severe, non X-linked congenital microcephaly with absence of the pyramidal tracts in two siblings.

Acta neuropathologica·1999
Same author

Itraconazole in the treatment of tinea pedis and tinea manuum: comparison of two treatment schedules.

Mycoses·1999
Same author

An alternative route for multistep tumorigenesis in a novel case of hereditary renal cell cancer and a t(2;3)(q35;q21) chromosome translocation.

American journal of human genetics·1998
Same author

Factors influencing participation among melanoma screening attenders.

Acta dermato-venereologica·1997
Same author

Quality assessment by expert opinion in melanoma pathology: experience of the pathology panel of the Dutch Melanoma Working Party.

The Journal of pathology·1997
Same author

Volunteer melanoma screenings. Follow-up, compliance, and outcome.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·1997
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Dermatology
  • Genetics
  • Anthropology

Background:

  • Naevocytic naevi (moles) are common skin lesions.
  • Previous studies suggest variations in mole counts across different populations.
  • Understanding these variations is crucial for dermatological research.

Purpose of the Study:

  • To investigate the relationship between racial background and the prevalence of naevocytic naevi.
  • To compare mole counts across diverse racial and ethnic groups.
  • To identify potential predisposing factors for mole development.

Main Methods:

  • Cross-sectional study design.
  • Quantitative analysis of mole counts in different racial groups (children and young adults).
  • Statistical comparison of median mole counts between groups.

Main Results:

  • White children had significantly more naevocytic naevi (17.0) than non-white children (2.5).
  • Young white adults also showed higher mole counts (61.0) compared to coloured subjects (16.0).
  • A gradient of decreasing mole counts was observed from white to Negroid descent.

Conclusions:

  • A strong racial predisposition to the development of naevocytic naevi exists.
  • Skin complexion and ancestry are significant factors in mole development.
  • Further research into the genetic mechanisms underlying these differences is warranted.

Related Experiment Videos