A H+/Ag+ dual-target responsive label-free light-up probe based on a DNA triplex

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Lijun Xu1, Yahui Guo, Jine Wang

  • 1Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123 (P.R. China); Department of Chemistry, Zhengzhou University, Zhengzhou, 450001 (P.R. China).

Chemistry, an Asian Journal
|February 10, 2015
PubMed

Keywords:
berberinelight-up probelogic gatesilvertriplex DNA

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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