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Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive

Muntecep Asker1, Selvi Asker2, Ugur Kucuk3

  • 1Department of Cardiology, Van Training and Research Hospital Van, Turkey.

International Journal of Clinical and Experimental Medicine
|February 10, 2015
PubMed

Insights

This study found a high prevalence of coronary artery disease in patients with chronic obstructive pulmonary disease and pulmonary hypertension. However, pulmonary hypertension was not found to be an independent risk factor for coronary artery disease presence or severity.

Area of Science:

  • Cardiology
  • Pulmonology
  • Internal Medicine

Background:

  • Pulmonary hypertension (PH) is common in patients with chronic obstructive pulmonary disease (COPD).
  • The relationship between PH and coronary artery disease (CAD) in COPD patients requires further investigation.

Purpose of the Study:

  • To investigate the association between PH and CAD in COPD patients.
  • To determine if PH is an independent risk factor for the presence and extent of CAD in this population.

Main Methods:

  • Retrospective analysis of 95 COPD patients with PH who underwent coronary angiography.
  • Patients were categorized based on the presence or absence of CAD.
  • Statistical comparisons included age, gender, comorbidities, and pulmonary function tests.

Main Results:

  • A high prevalence of CAD was observed in COPD patients with PH.
  • Male gender and hypertension were positively correlated with CAD presence.
  • FEV1/FVC ratio and systolic pulmonary artery pressure (sPAP) showed negative correlation with CAD presence.

Conclusions:

  • COPD patients with PH exhibit a high rate of concurrent CAD.
  • PH is not identified as an independent risk factor for CAD presence or severity in this cohort.
  • Further research is needed to elucidate the complex interplay between these conditions.

Keywords:
Coronary artery diseasechronic obstructivehypertensionpulmonarypulmonary disease

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