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Relationship between periodontal diseases and preterm birth: Recent epidemiological and biological data
1Department of Gynecology and Obstetrics, Christian Medical College, Ludhiana, Punjab, India.
Insights
Maternal periodontal disease is linked to preterm birth. Early detection and treatment of gum disease in pregnant women can help prevent premature delivery, especially for those at high risk.
Area of Science:
- Obstetrics and Gynecology
- Periodontology
- Public Health
Background:
- Preterm birth affects approximately 9.6% of global births, with significant regional variations.
- A link between maternal periodontal disease and preterm birth was first reported in 1996.
- Despite efforts, preterm birth rates remain a concern worldwide.
Purpose of the Study:
- To review current epidemiological and biological data on the relationship between maternal periodontal disease and preterm birth.
- To explore the mechanisms by which periodontal bacteria may impact pregnancy outcomes.
Main Methods:
- Literature search conducted on Google and PubMed, focusing on recent articles.
- Review of epidemiological and biological data linking periodontal disease to pregnancy outcomes.
Main Results:
- Three primary hypotheses explain how periodontal bacteria may affect pregnancy: bacterial spreading, inflammatory product dissemination, and fetomaternal immune response.
- Evidence suggests a connection between maternal oral health and the risk of preterm delivery.
Conclusions:
- Early detection and treatment of periodontal disease in women of reproductive age, before and during pregnancy, are crucial.
- Interventions targeting periodontal health may reduce the incidence of preterm birth, particularly in at-risk populations.
Abstract:
Preterm infants are born prior to completion of 37 weeks of gestation. These patients are seen on the rise despite the efforts put in to control them. Global incidence of preterm birth is around 9.6% of all birth representing 12.9 million births with regional disparities: From 12% to 13% in USA, from 5% to 9% in Europe, and 18% in Africa. First reported by Offenbacher et al. in 1996 relationship exist between maternal periodontal disease and delivery of a preterm infant. This article reviews the recent epidemiological and biological data. The articles were searched on Google, PubMed recent articles were selected. Mainly, three hypotheses by which periodontal bacteria can affect the outcome of pregnancy. Biological hypothesis: (a) Bacterial spreading, (b) Inflammatory products dissemination, (c) Role of fetomaternal immune response against oral pathogens. The promotion of the early detection and treatments of periodontal disease in young women before and during pregnancy will be beneficial especially for women at risk.
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