Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

709
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
709
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

1.4K
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.4K
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

2
A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
2
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

709
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
709
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.4K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.4K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

672
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
672

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic Significance of Electrocardiographic Findings in Hemodynamically Stable Patients With Acute Pulmonary Embolism: Insights From the RIETE Registry.

Archivos de bronconeumologia·2026
Same author

A simple score to identify the sickest normotensive patients with acute pulmonary embolism.

ERJ open research·2026
Same author

Development and external validation of an international score to predict cancer 1 year after venous thromboembolism.

European journal of internal medicine·2026
Same author

Fatal Pulmonary Embolism in Professional Athletes: A Window Into a Broader VTE Problem.

Journal of the American College of Cardiology·2026
Same author

Oxygen saturation and mortality for acute pulmonary embolism: multinational retrospective cohort study.

EClinicalMedicine·2026
Same author

Pyridine-boryl radical mediated synthesis of quinolines <i>via</i> α-amino radical formation and intramolecular alkenyl sulfone trapping.

Organic chemistry frontiers : an international journal of organic chemistry·2026
Same journal

Mediastinal amyloidosis mimicking advanced lung cancer.

Thorax·2026
Same journal

Comparative performance of endobronchial ultrasound-guided sampling techniques in patients with mediastinal lesions: a network meta-analysis.

Thorax·2026
Same journal

Vitamin A and D impact on lung function: differential or common effects across the lifespan?

Thorax·2026
Same journal

The impact of vitamins A and D on lung function and regulatory epigenetics in adult and childhood asthma.

Thorax·2026
Same journal

Radiological factors associated with the recurrence of <i>Mycobacterium avium complex</i> pulmonary disease: a multicentre retrospective cohort study.

Thorax·2026
Same journal

Daughter vesicles in primary diaphragmatic hydatid cyst.

Thorax·2026
See all related articles

Related Experiment Video

Updated: Apr 17, 2026

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit
08:22

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit

Published on: December 12, 2025

1.5K

Computerised clinical decision support for suspected PE.

David Jiménez1, Santiago Resano2, Remedios Otero3

  • 1Respiratory Department, Ramón y Cajal Hospital, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, and Alcala de Henares University, Madrid, Spain.

Thorax
|February 11, 2015
PubMed
Summary
This summary is machine-generated.

Clinical decision support (CDS) algorithms reduced CT pulmonary angiography (CTPA) use in emergency departments. This improved diagnostic yield and decreased venous thromboembolic events in patients initially testing negative for pulmonary embolism (PE).

Keywords:
Pulmonary Embolism

More Related Videos

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

991
Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

17.2K

Related Experiment Videos

Last Updated: Apr 17, 2026

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit
08:22

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit

Published on: December 12, 2025

1.5K
A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

991
Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

17.2K

Area of Science:

  • Emergency Medicine
  • Radiology
  • Clinical Informatics

Background:

  • Pulmonary embolism (PE) diagnosis often involves CT pulmonary angiography (CTPA).
  • Overutilization of CTPA can lead to increased costs and radiation exposure.
  • Clinical decision support (CDS) tools may optimize diagnostic pathways.

Purpose of the Study:

  • To evaluate the impact of an evidence-based CDS algorithm on CTPA utilization and outcomes.
  • To assess the effect of CDS on patients evaluated for suspected PE in the emergency department (ED).

Main Methods:

  • A retrospective study of 1363 patients evaluated for suspected PE in an ED.
  • Data collected over 12 months before and 12 months after CDS implementation.
  • Analysis focused on CTPA use, diagnostic yield, and patient outcomes.

Main Results:

  • Introduction of CDS was associated with a significant decrease in CTPA use (55% vs. 49%, p=0.02).
  • Fewer symptomatic venous thromboembolic events occurred during follow-up in patients with initially negative diagnostic evaluations (0.7% vs. 3.2%, p<0.01).
  • The study demonstrated improved diagnostic accuracy and patient safety.

Conclusions:

  • Evidence-based CDS algorithms can effectively reduce unnecessary CTPA utilization in the ED.
  • CDS implementation is linked to improved patient outcomes, including fewer thromboembolic events.
  • CDS tools represent a valuable strategy for optimizing PE diagnostic workflows.