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Present understanding of the relationship between exercise and arrhythmogenic right ventricular

Anne Rojas1, Hugh Calkins1

  • 1Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

Trends in Cardiovascular Medicine
|February 11, 2015
PubMed

Insights

Exercise can worsen arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C), an inherited heart condition. Patients with ARVD/C should avoid competitive sports and limit physical activity to reduce risks.

Area of Science:

  • Cardiology
  • Genetics
  • Sports Medicine

Background:

  • Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited heart disease.
  • It involves fibrofatty myocardial replacement, leading to arrhythmias and sudden death.
  • A connection between exercise and ARVD/C has long been observed.

Purpose of the Study:

  • To review evidence linking exercise to ARVD/C development and outcomes.
  • To inform clinical recommendations for patients with ARVD/C regarding physical activity.

Main Methods:

  • Review of epidemiologic data.
  • Analysis of basic science research.
  • Evaluation of clinical research findings.

Main Results:

  • Substantial evidence supports a link between exercise and ARVD/C.
  • Exercise appears to influence disease progression and patient outcomes.
  • Data indicate exercise exacerbates ARVD/C pathology.

Conclusions:

  • Patients diagnosed with ARVD/C should avoid competitive athletic activities.
  • Limiting physical exercise is strongly advised for individuals with ARVD/C.

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