Related Experiment Video
Updated: Apr 17, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
[Bilateral simultaneous central retinal vein occlusion in protein S deficiency]
G Tóth1, G L Sándor2, C Reichel3
1Augenklinik, Semmelweis Universität, Mária u. 39, 1085, Budapest, Ungarn. gabortothgabor@gmail.com.
Case Report:
This article reports a case of bilateral simultaneous central retinal vein occlusion (CRVO) and protein S deficiency. The 27-year-old male patient presented with a sudden decrease in vision in both eyes. The patient's medical history documented the death of his father at the age of 33 years due to pulmonary embolism. Thrombophilia screening revealed protein S deficiency.
Objectives:
We report this case to emphasize that in any case of young onset retinal vein occlusion, protein S deficiency should be suspected.
Conclusions:
Thrombophilia assays and taking a thorough medical history should be performed.
Related Concept Videos
Diabetic Retinopathy
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Photoreceptors and Visual Pathways
Nephrotic Syndrome II : Assessment and Medical Management
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...

