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Related Concept Videos

Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

941
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
941
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

360
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
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Related Experiment Video

Updated: Apr 17, 2026

Robotic-assisted Lateral Pancreaticojejunostomy for Chronic Pancreatitis
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Robotic-assisted Lateral Pancreaticojejunostomy for Chronic Pancreatitis

Published on: September 5, 2025

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Alvimopan: A cost-effective tool to decrease cystectomy length of stay.

Jules Powers Manger1, Marc Nelson1, Shawnna Blanchard1

  • 1University of Virginia, Department of Urology, Charlottesville, USA.

Central European Journal of Urology
|February 11, 2015
PubMed
Summary
This summary is machine-generated.

Perioperative alvimopan use in cystectomy and urinary diversion significantly reduced length of stay by 1.9 days and lowered costs by $7,062 per admission. This study confirms alvimopan

Keywords:
alvimopanbladder cancercost–effectivenesscystectomylength–of–stayurinary diversion

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Area of Science:

  • Urology
  • Surgical Outcomes
  • Health Economics

Background:

  • Alvimopan's efficacy in reducing postoperative ileus and length of stay after cystectomy was previously shown, but excluded epidural analgesia.
  • Cost-effectiveness of perioperative alvimopan in cystectomy and urinary diversion requires evaluation.

Purpose of the Study:

  • To evaluate the cost-effectiveness of perioperative alvimopan in patients undergoing cystectomy and urinary diversion.
  • To assess the impact of alvimopan on length of stay and hospital costs in this patient population.

Main Methods:

  • Retrospective analysis of 86 cystectomy and urinary diversion procedures.
  • Comparison between 50 patients not receiving alvimopan and 36 patients receiving perioperative alvimopan.

Main Results:

  • Alvimopan group had a significantly shorter length of stay (8.6 days vs. 10.5 days).
  • Readmission rates for ileus were low in both groups (0% vs. 4.4%).
  • Alvimopan use resulted in significantly lower costs ($32,443 vs. $40,604), a difference of $7,062 per admission.

Conclusions:

  • Routine perioperative alvimopan decreased length of stay by 1.9 days in cystectomy and urinary diversion patients.
  • Perioperative alvimopan reduced costs by $7,062 per admission, representing a 20% reduction.
  • Demonstrates real-world application and cost-effectiveness of alvimopan in a moderate-volume center.