Related Experiment Video
Updated: Apr 17, 2026

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
Placental dichotomy: a hint in twin anemia polycythemia sequence
Amelie Stritzke1, Sumesh Thomas1, David Somerset2
1Department of Paediatrics, Neonatology Section, University of Calgary, Calgary AB.
Background:
Monochorionic pregnancies are a significant part of the workload in diagnostic imaging, and must be assessed frequently for the detection of twin-twin transfusion syndrome. Recognizing placental dichotomy at the time of routine fetal cerebral artery Doppler screening is important for alerting the clinician to potential twin anemia polycythemia sequence, an important subset of feto-fetal transfusions.
Case:
A 36-year-old multigravid woman with a twin pregnancy delivered at 33 weeks' gestation after fetal distress was identified. Twin anemia polycythemia sequence was diagnosed after delivery. Regular prenatal ultrasound scans had not identified oligo- or polyhydramnios. Retrospective assessment of the ultrasound images of the placenta showed marked dichotomy, with the anemic twin's portion being hyperechogenic.
Conclusion:
Identification of placental dichotomy, in addition to screening with cerebral Doppler flow studies, may lead to earlier identification of twin anemia polycythemia sequence and improved outcomes.
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