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Updated: Apr 17, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
[Treatment-resistant depression: state of the art Part II. Treatment]
Aim:
This work would give an overall and up-to-date vision of psychopharmacological and physical strategies of treatment for resistant depression.
Method:
A PubMed search was done using the keywords "resistant depression treatment", "electroconvulsive therapy", "antidepressants", and the inclusion criteria of adult samples, English, French or Italian languages.
Results:
Lots of psycho-pharmacological and physical treatment strategies for resistant depression exist; anyway there is no consensus about their indications and efficacy, which appears still unsatisfactory.
Discussion And Conclusion:
Further research should move towards the identification of specific clinical picture of treatment resistant depression to develop more efficacious and selective treatment protocols.
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