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Updated: Apr 17, 2026

Training Rats to Voluntarily Dive Underwater: Investigations of the Mammalian Diving Response
Published on: November 12, 2014
[Changes of cerebral blood flow during diving reactions in humans]
Abstract:
The characteristics of human cerebral blood flow were estimated during the implementation of the diving response, simulated by complex cold-hypoxic-hypercapnic exposure (CHHE), and under the influence of separate cold, hypercapnic and hypoxic stimuli. Was studied 18 people aged 18-22 years who had no special training. Cerebral blood flow was recorded by transcranial Doppler. It is shown that in the CHHE with the respect initial state to observe a marked increase in cerebral blood flow linear velocity (BFV) to 82.3 ± 15.2%, as well as reducing characterizing the tone of resistance vessels of the brain pulsatility index (PI) to 77.2 ± 13.1%. During cold and tactile stimulation of facial skin BFV and PI did not change significantly, with a single breath hold (Genchi test) BFV increased by 52.3 ± 12.5%, PI at 64.5 ± 15%. The latent period of cerebral blood flow (14-43) allow suppose metabolic (chemical) nature of regulatory influences, which provide changes of considered indicators.
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