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Squamous Cell Carcinoma With Chronic Osteomyelitis: A Case Report.
Spencer J Monaco1, Kyle Pearson2, Dane K Wukich2
1University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania monacosj2@upmc.edu.
Foot & Ankle Specialist
|February 12, 2015
Summary
Squamous cell carcinoma (SCC) is rare in the lower extremity. This case report highlights SCC developing in chronic osteomyelitis, emphasizing the need for vigilance in wound care to prevent malignant degeneration.
Area of Science:
- Oncology
- Dermatology
- Orthopedic Surgery
Background:
- Squamous cell carcinoma (SCC) is a common malignancy but rarely occurs in the lower extremity.
- Chronic wounds, particularly osteomyelitis, pose a risk for malignant transformation.
- Early diagnosis and treatment of lower extremity SCC are crucial to prevent patient harm.
Observation:
- A case of squamous cell carcinoma co-occurring with chronic osteomyelitis in a lower extremity is presented.
- The patient had no history of diabetes, a common comorbidity in lower extremity wound cases.
- Diagnosis was delayed, underscoring the need for vigilance in non-healing wounds.
Findings:
- Definitive treatment involved transtibial amputation.
- Metastatic workup revealed no evidence of active malignancy beyond the primary tumor site.
- The SCC developed in the context of chronic osteomyelitis.
Implications:
- Surgeons managing chronic lower extremity wounds must be aware of the potential for malignant transformation.
- Prompt surgical intervention is necessary for SCC of the lower extremity to improve patient outcomes.
- This case emphasizes the importance of considering malignancy in non-healing chronic wounds, irrespective of comorbidities like diabetes.
