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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
793
Medication adherence interventions for heart failure patients: A meta-analysis
Todd M Ruppar1, Janet M Delgado2, Jonathon Temple3
1Sinclair School of Nursing, University of Missouri, Columbia, USA RupparT@missouri.edu.
European Journal of Cardiovascular Nursing
|February 12, 2015
Summary
Improving heart failure medication adherence is crucial for patient self-care. Interventions focused solely on patient behavior showed modest but significant improvements in medication adherence outcomes.
Area of Science:
- Cardiology
- Pharmacology
- Health Services Research
Background:
- Medication adherence is vital for heart failure self-care.
- Poor adherence increases exacerbations, hospitalizations, and mortality.
- Effective interventions are needed to improve patient outcomes.
Purpose of the Study:
- To quantify the impact of interventions on heart failure medication adherence.
- To identify factors influencing intervention effectiveness.
Main Methods:
- Systematic literature search for medication adherence interventions in heart failure.
- Random-effects meta-analysis of 29 studies (n=4285).
- Meta-regression and ANOVA used for moderator analyses.
Main Results:
- A significant, modest mean effect size (d=0.29) for interventions.
- Larger effect sizes observed in older populations and studies from Europe/Asia.
- Interventions focused solely on medication adherence yielded greater effects.
Conclusions:
- Interventions to improve heart failure medication adherence are effective but modest.
- Focusing interventions on patient behavior and medication adherence alone appears most beneficial.
- Future strategies should prioritize patient-centered, adherence-focused approaches.
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