Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

473
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
473
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

2.1K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
2.1K
Routes of Drug Administration: Parenteral01:25

Routes of Drug Administration: Parenteral

3.9K
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
3.9K
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

1.8K
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
1.8K
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

2.8K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
2.8K
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

398
Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
398

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing encephalitis.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2017
Same author

In-hospital resuscitation.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2016
Same author

Pulmonary oedema.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2016
Same author

Ascites.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2014
Same author

Acute confusion.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2014
Same author

Temperature monitoring.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2014

Related Experiment Video

Updated: Apr 17, 2026

Delivery of Therapeutic Agents Through Intracerebroventricular ICV and Intravenous IV Injection in Mice
05:55

Delivery of Therapeutic Agents Through Intracerebroventricular ICV and Intravenous IV Injection in Mice

Published on: October 3, 2011

64.2K

Intravenous therapy.

Abby Morrow-Barnes1

  • 1Warwick Hospital, England.

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|February 12, 2015
PubMed
Summary
This summary is machine-generated.

Intravenous therapy in older adults presents unique difficulties due to age-related physiological changes and multiple health conditions. These factors complicate treatment delivery and patient care.

More Related Videos

Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema
08:44

Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema

Published on: September 1, 2016

9.4K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.7K

Related Experiment Videos

Last Updated: Apr 17, 2026

Delivery of Therapeutic Agents Through Intracerebroventricular ICV and Intravenous IV Injection in Mice
05:55

Delivery of Therapeutic Agents Through Intracerebroventricular ICV and Intravenous IV Injection in Mice

Published on: October 3, 2011

64.2K
Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema
08:44

Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema

Published on: September 1, 2016

9.4K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.7K

Area of Science:

  • Gerontology
  • Vascular Medicine
  • Pharmacology

Background:

  • Older adults often have comorbidities that complicate medical treatments.
  • Age-related changes affect skin integrity and venous access.
  • Intravenous (IV) therapy is a common but challenging procedure in geriatric care.

Purpose of the Study:

  • To identify and describe the specific challenges associated with providing intravenous therapy to the geriatric population.
  • To highlight the impact of comorbidities and age-related physiological changes on IV access and management.

Main Methods:

  • Literature review of studies on geriatric IV therapy.
  • Analysis of physiological changes in aging skin and veins.
  • Examination of common comorbidities in older patients.

Main Results:

  • Reduced skin elasticity and subcutaneous fat in older adults can make vein identification and cannulation difficult.
  • Vascular changes may lead to increased risk of infiltration or phlebitis.
  • Comorbidities such as diabetes and peripheral vascular disease further complicate IV access and management.

Conclusions:

  • Intravenous therapy in older individuals requires specialized approaches to mitigate risks.
  • Understanding age-related vascular and skin changes is crucial for successful IV therapy.
  • Careful patient assessment and technique are essential for safe and effective geriatric IV administration.