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[The effect of gamma rays on medazepam in a methanolic solution]
Pharmaceutica Acta Helvetiae
|January 1, 1989
Abstract:
Nine radiolytical products have been identified in a methanolic solution of Medazepam exposed to gamma-irradiation. A decomposition model taking into account these radiolytical products is presented. The formation of the individual radiolytical products can be deduced from analogous reactions of the radicals e-sdv., H, CH2OH, OH and HO2/O2- with several substances. Based on this knowledge of the radiochemical behaviour of Medazepam scavenger systems against radiolysis in solution can be developped.