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Bolaamphiphiles: a pharmaceutical review
Mayur Fariya1, Ankitkumar Jain1, Vivek Dhawan1
1Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Santacruz (E), Mumbai - 400098, India.
Abstract:
The field of drug discovery is ever growing and excipients play a major role in it. A novel class of amphiphiles has been discussed in the review. The review focuses on natural as well as synthetic bolaamphiphiles, their chemical structures and importantly, their ability to self assemble rendering them of great use to pharmaceutical industry. Recent reports on their ability to be used in fabrication of suitable nanosized carriers for drug as well as genes to target site, has been discussed substantially to understand the potential of bolaamphiphiles in field of drug delivery.
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