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Related Concept Videos

Skin Cancer01:30

Skin Cancer

6.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Mutations01:35

Mutations

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
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Mutations01:39

Mutations

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Overview
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Cancer Prevention02:59

Cancer Prevention

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Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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Related Experiment Video

Updated: Apr 17, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

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Sunscreens causing cancer? The facts.

Sheila Jalalat1

  • 1sjalalat@gmail.com.

Cutis
|February 12, 2015
PubMed
Summary

Sunscreen safety claims are widespread, but evidence suggests the benefits of sun protection outweigh potential risks. This analysis critically examines data to inform patient guidance on sunscreen use.

Area of Science:

  • Dermatology
  • Public Health
  • Toxicology

Background:

  • Widespread media reports question sunscreen safety, citing cancer risks.
  • Public concern is high regarding the safety of sunscreen products.

Purpose of the Study:

  • To critically analyze the evidence regarding sunscreen safety concerns.
  • To evaluate whether the risks of sunscreen use outweigh the benefits.
  • To provide guidance for dermatologists advising patients on sunscreen.

Main Methods:

  • Literature review of evidence-based data on sunscreen safety.
  • Critical analysis of scientific reports and media claims.
  • Synthesis of current understanding of sunscreen risks and benefits.

Main Results:

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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

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Studying Chronic Exposure of Mice to Ultraviolet B Radiation
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  • Analysis indicates that current evidence does not support claims that sunscreens cause cancer.
  • The protective benefits of sunscreens against harmful UV radiation are well-established.
  • Potential risks associated with sunscreen ingredients are generally considered minimal compared to sun damage.

Conclusions:

  • The available evidence supports the continued recommendation of sunscreen use for skin cancer prevention.
  • Dermatologists should address patient concerns by providing accurate, evidence-based information.
  • Further research may be needed, but current data favor sunscreen use.