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Antifungal effects of root canal irrigants and medicaments. An update review

Zahed Mohammadi, Sousan Shalavi

    The New York State Dental Journal
    |February 13, 2015
    PubMed

    Insights

    This review examines the antifungal effectiveness of common endodontic irrigants and medicaments, focusing on their role in combating persistent fungal infections like Candida albicans in root canals.

    Area of Science:

    • Endodontics
    • Mycology
    • Infectious Diseases

    Background:

    • Fungal infections, particularly Candida albicans, are implicated in persistent and secondary endodontic infections.
    • Effective management of these infections requires understanding the antifungal properties of available endodontic agents.

    Purpose of the Study:

    • To review and compare the antifungal activity of various endodontic irrigants and medicaments.
    • To provide insights into agent selection for managing fungal endodontic infections.

    Main Methods:

    • Literature review of studies evaluating antifungal efficacy.
    • Analysis of data on sodium hypochlorite, chlorhexidine, MTAD, Tetraclean, EDTA, calcium hydroxide, and MTA.

    Main Results:

    • The review synthesizes existing data on the antifungal spectrum and potency of each agent.
    • Comparative analysis highlights variations in efficacy against Candida albicans and other relevant fungi.

    Conclusions:

    • Understanding the comparative antifungal activity of irrigants and medicaments is crucial for successful endodontic treatment.
    • Evidence-based selection of agents can improve outcomes in managing persistent fungal endodontic infections.

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