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Linkage data on affective disorders in an epidemiologic context
1Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
Genetic Epidemiology
|January 1, 1989
Abstract:
Recent data on chromosomal linkage markers in affective disorders indicate that single locus inheritance is involved in these disorders. The presence of a single locus has not been detectable using segregation analysis on family study data from large populations, possibly because of both heterogeneity and birth cohort and sex differences in diagnostic frequencies.